We've known for a long time that Conan O'Brien will be at San Diego Comic-Con this year. He's just announced that he's going to break with his long-standing show tradition and air new shows on Wednesday, Thursday, Friday and Saturday.
He also tantalized the audience by promising that "All of our comedy and all of our guests are going to relate to the magic of Comic-Con." This could be something to make your parents and non-nerd friends watch so they understand just what it is you get up to in San Diego every July. On the other hand, it's probably going to inspire a new 394,723 people to sign up for Member IDs, so there's that.
First-timers, don't bank on watching this in your hotel room each night - it's highly possible you'll be out at an event or already snoring in bed. So you might want to set your DVR if you're interested in seeing these episodes.
As far as getting tickets - this is where you can normally go for Conan tickets. They're free and they go fast. The SDCC shows aren't on the site yet and I'm not entirely sure they'll be handled the same way. If you'd like to attend one of these shows, I'd suggest monitoring the site closely and applying the same obsessive focus you used to get your SDCC badge, because it will be almost as competitive.